How Revatio Helps People Treat Hypertension

pulmonary arterial hypertensionRevatio is a popular oral medication that contains sildenafil citrate as its active ingredient, and it’s approved to be taken to treat pulmonary arterial hypertension. The main goal of this therapy is improving people’s exercise ability and postponing their clinical worsening. Check sildenafil citrate 20 mg reviews and research studies that prove the effectiveness of Revatio for most patients with this condition.

Basic Information about Pulmonary Hypertension

Basically, it’s a form of high blood pressure that has an impact on the arteries in lungs and the right side of the heart. In one of its forms, tiny lung arteries, known as pulmonary arterioles, and capillaries are blocked, narrowed and even destroyed, thus, making it much harder for the blood to flow via lungs and raising pressure within their arteries. As pressure raises, the lower right chamber of the heart needs to work harder to pump enough blood through lungs, thus, making heart muscles fail and weaken. Some forms of this condition are serious, and they may become worse and even fatal, while others aren’t curable. The right treatment helps patients improve the quality of their lives and lessen unwanted symptoms, so read more about Revatio and pulmonary arterial hypertension.

How Revatio Works to Treat Hypertension

Revatio contains sildenafil citrate that belongs to a group of drugs called PDE-5 inhibitors. PDE-5 is a certain substance produced in lungs and other body parts naturally, and it breaks down cGMP. The latter one causes arteries and blood vessels to widen and relax, so the intake of sildenafil citrate helps patients reduce the PDE-5 activity in their bodies, so that cGMP is not destroyed in their arteries inside lungs. This pharmaceutical effect results in widening and relaxation of these blood vessels and decreasing pulmonary blood pressure to people’s heart while improving its functioning. There are many research studies and clinical tests that prove the positive effects of the use of Revatio for treating this condition. It’s a well-known and effective prescription medication that contains sildenafil citrate, and it’s often prescribed by doctors to help their adult patients treat pulmonary arterial hypertension. When taking this drug exactly as directed, it does the following:

  • Improving people’s ability to exercise;
  • Slowing down the worsening changes of their physical condition.

Clinical Trials of Revatio

First, this medicine was approved by the FDA to treat pulmonary arterial hypertension in 2005. A few years later, the FDA also approved its intravenous form. Those important approvals were given after a series of successful and detailed clinical trials and tests with the data that proved positive effects of the intake of Revatio by patients with pulmonary arterial hypertension. That’s because it improved their exercising abilities and slowed down the rates of disease progression. However, this medication shouldn’t be taken by children

The right dosage of this drug ranges from 5 to 20 mg, and it’s based on the severity of patients’ medical condition and their individual tolerance. They need to take Revatio orally 3 times a day, with a 4-6-hour break. If they can’t take this medicine orally, it’s advisable to switch to its intravenous form that must be administered 3 times a day.